Psychopharmacological Approaches to Treatment

Psychopathology | Psychological syndrome | Psychiatry Journal

Psychopharmacological Approaches to Treat Psychopathology

Instructions:

To Prepare:

Review the Learning Resources for this week in preparation to complete this Assignment.

Reflect on the basic function and structure of the neuron in relation to the central nervous system.

Reflect on the inter-connectedness between neurons and the central nervous system, including the pathway and distribution of electrical impulses.

Reflect on how neurons communicate with each other and review the concept of neuroplasticity.

In 4 or 5 sentences, describe the anatomy of the basic unit of the nervous system, the neuron. Include each part of the neuron and a general overview of electrical impulse conduction, the pathway it travels, and the net result at the termination of the impulse. Be specific and provide examples.

Answer the following (listing is acceptable for these questions):

What are the major components that make up the subcortical structures?

Which component plays a role in learning, memory, and addiction?

What are the two key neurotransmitters located in the nigra striatal region of the brain that play a major role in motor control?

In 3 or 4 sentences, explain how glia cells function in the central nervous system. Be specific and provide examples.

The synapse is an area between two neurons that allows for chemical communication. In 3 or 4 sentences, explain what part of the neurons are communicating with each other and in which direction does this communication occur? Be specific.

In 3–5 sentences, explain the concept of “neuroplasticity.” Be specific and provide examples.

Camprodon, J. A., & Roffman, J. L. (2016). Psychiatric neuroscience: Incorporating pathophysiology into clinical case formulation. In T. A. Stern, M. Favo, T. E. Wilens, & J. F. Rosenbaum. (Eds.), Massachusetts General Hospital psychopharmacology and neurotherapeutics (pp. 1–19). Elsevier.

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Take medication safely Term Paper

Take medication safely
Take medication safely

Take medication safely ( preventing medication errors)

. Select a Speak Up brochure developed by The Joint Commission. Follow this link to the proper
website: https://www.jointcommission.org/topics/speak_up_campaigns.aspx
2. Write a short paper reviewing the brochure. Use the Grading Criteria (below) to structure your critique
and include current nursing or healthcare research to support your critique.
a. The length of the paper is to be no greater than three pages, double spaced, excluding title
page and reference page. Extra pages will not be read and will not count toward your grade.
3. This assignment will be graded on quality of information presented, use of citations, and use of
Standard English grammar, sentence structure, and organization based on the required component
6. APA format is required with both a title page and reference page. Use the required components of the
review as Level 1 headers (upper- and lowercase, bold, centered).
a. Introduction
b. Summary of Brochure
c. Evaluation of Brochure
d. Conclusion

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Physical Hazards Control Read the OSHA

Physical Hazards Control Read the OSHA inspection report below. The company was cited for 4 serious violations and 1 repeat violation.

Physical Hazards Control Read the OSHA
Physical Hazards Control Read the OSHA

Explain OSHA is the definition of a serious violation and repeat violation.

Find the OSHA standards that were cited and provide the language OSHA uses for each.

Employed by ABC Company, Robert Martin and another man were on the lift working when it suddenly lurched forward and pinned Martin between its control panel and the edge of the roof. The 35-year-old foreman and father of three were pronounced dead at the scene. His co-worker was able to crawl out of the lift’s basket and then fell nearly three stories, suffering multiple fractures in his left leg.

The workers were rehabilitating a Chevy dealership on Apple City.

OSHA opened its investigation upon learning of the fatal incident. On March 23, 2016, the agency issued citations to ABC Company for one repeated and four serious safety violations. Proposed penalties total $63,900.

ìABC Company could have prevented this tragedy by simply inspecting the lift before allowing its workers to use it,” said Brian Sturtecky, director of OSHA’s Jacksonville Area Office. “This company must immediately address safety hazards at its work sites and be vigilant in the future to protect its employees from harm.”

OSHA issued one repeated citation for not ensuring that workers wore and attached a body belt or lanyard while using an aerial lift.

The serious citations related to the following OSHA standards:

29 CFR 1904 Section 5(a)(1)

29 CFR 1926.300(b)(1)

29 CFR 1926.404(f)(6)

29 CFR 1926.453(b)(2)(i)

The repeat citation related to the following OSHA standard:

29 CFR 1926.453(b)(2)(v)

Morphine effects, adverse effects, and contraindications

Morphine effects, adverse effects, and contraindications
         Morphine effects, adverse effects, and                                         contraindications

Morphine effects, adverse effects, and contraindications

Always review the assigned readings for the week before developing your discussion. Always include references in at the end of your discussion. Do not copy and post as it is in your text book, paraphrase in your own words to indicate that you understood what you read.
Write a discussion to explain;

1. Sumatriptan including its side effects, adverse effects, and contraindications
2. Morphine including its side effects, adverse effects, and contraindications
3. Quetiapine including its side effects, adverse effects, and contraindications

Resources
Richard A. Lehne (2013). Pharmacology for Nursing care (8th ed.). ISBN: 978143773586
Chapter 28-Opioid analgesics & antagonists

Morphine; pages 275-281
Fentanyl; pages 281-283
Meperidine; page 284
Methadone; page 284
Codeine; page 285-286
Patient controlled analgesic (PCA); pages 290-291
Opioid antagonist-Naloxone (Narcan); pages 292-293
Chapter 30-Drugs for headache

Ergotamine; pages 321-323
Dihydroergotamine; page 323
Sumatriptan; pages 323-325
Chapter 31-Antipsychotic agents

Table 31-4; page 336
Extrapyramidal symptoms; pages 337-338
Neuroleptic malignant syndrome; pages 338-339
Haloperidol; page 340 (Study everything about this drug)
Clozapine; pages 341-343
Risperidone; page 343
Olazapine; pages 343-344
Quetiapine; pages 343-345
Aripiprazole; page 345

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Neurochemistry and Neurotransmitter Function

Neurochemistry and Neurotransmitter Function Part One
What is meant by the neurochemistry of a drug? Identify one neurotransmitter and describe its physiological function in the human brain.

Neurochemistry and Neurotransmitter Function
Neurochemistry and Neurotransmitter Function

Provide an example to support your description.
This discussion question meets the following CACREP Standard: 5.C.2.g. Impact of biological and neurological mechanisms on mental health.
Part Two
Objectives:
Discuss the effects of addiction on the components of the central nervous system and other organ systems in the human body.
Examine the different neurotransmitters in the brain.
Describe the process of neurotransmission. Cholinergic functions, which are quantitatively minor among other brain neurotransmitters, are studied intensively because of this hypothesis.

Pharmacotherapy for Hematologic Disorders

Pharmacotherapy for Hematologic Disorders In the 1970s, the average lifespan for patients diagnosed with sickle cell disease was 14 years. Today, the average lifespan has increased to 50 years and beyond (TriHealth, 2012).

Pharmacotherapy for Hematologic Disorders
Pharmacotherapy for Hematologic Disorders

The patient prognosis for many other hematologic disorders such as hemophilia and cancer continue to improve as well. This can be attributed to advancements in medical care—specifically drug therapy and treatment.

Pharmacotherapy for Hematologic Disorders in Clinical Settings

When managing drug therapies for patients, it is essential to continuously examine current treatments and evaluate the impact of patient factors on drug effectiveness. To prepare for your role as an advanced practice nurse, you must become familiar with common drug treatments for various hematologic disorders seen in clinical settings.
To prepare:
• Select one of the following hematologic disorders: anemia, hemophilia, cancer, sickle cell anemia, thalassemia, thrombolytic disorders, or white blood cell disorders. Consider the types of drugs that would be prescribed to patients to treat symptoms associated with this disorder.
• Select one of the following factors: genetics, gender, ethnicity, age, or behavior. Reflect on how this factor might impact the effects of prescribed drugs, as well as any measures you might take to help reduce negative side effects.
With these thoughts in mind:
Post a description of the hematologic disorder you selected including types of drugs that would be prescribed to patients to treat associated symptoms. Then, explain how the factor you selected might impact the effects of prescribed drugs, as well as any measures you might take to help reduce negative side effects.
Week 10: Women’s and Men’s Health
Breast cancer is not just a disease that strikes at women. It strikes at the very heart of who we are as women: how others perceive us, how we perceive ourselves, how we live, work, and raise our families—or whether we do these things at all.
–Debbie Wasserman Schultz
This sentiment that Schultz expressed is true for many disorders associated with women’s and men’s health such as hormone deficiencies, cancers, and other functional and structural abnormalities.

Pharmacotherapy for Hematologic Disorders and Physiological Consequences

Disorders such as these not only result in physiological consequences but also psychological consequences such as embarrassment, guilt, or profound disappointment for patients. For these reasons, the provider-patient relationship must be carefully managed. During evaluations, patients must feel comfortable answering questions so that you, as a key health-care provider, will be able to diagnose and recommend appropriate treatment options. Advanced practice nurses must be able to educate patients on these disorders and help relieve associated stigmas and concerns.
This week, as you examine women’s and men’s health issues, you focus on treatments for hormone deficiencies and cancer. You also explore preventive services for women’s and men’s health.
Learning Objectives
students will:
Evaluate the strengths and limitations of hormone replacement therapy
Evaluate treatments for hormone deficiencies
Analyze preventive services for women’s and men’s health
Analyze drug treatments for cancer patients
Evaluate implications of cancer drug treatments on patients
Understand and apply key terms, concepts, and principles related to prescribing drugs to treat disorders associated with women’s and men’s health
Photo Credit: Comstock/Stockbyte/Getty Images
Learning Resources
This page contains the Learning Resources for this week. Be sure to scroll down the page to see all of this week’s assigned Learning Resources. To access select media resources, please use the media player below.

Pharmacotherapy for Hematologic Disorders Required Readings

Arcangelo, V. P., Peterson, A. M., Wilbur, V., & Reinhold, J. A. (Eds.). (2017). Pharmacotherapeutics for advanced practice: A practical approach (4th ed.). Ambler, PA: Lippincott Williams & Wilkins.
Chapter 33, “Prostatic Disorders and Erectile Dysfunction” (pp. 527-544)
This chapter examines the causes, pathophysiology, and drug treatment of four disorders: prostatitis, benign prostatic hyperplasia, prostate cancer, and erectile dysfunction. It also explores the importance of monitoring patient response and patient education.
Chapter 34, “Overactive Bladder” (pp. 545-564)
This chapter describes the causes, pathophysiology, diagnostic criteria, and evaluation of overactive bladder. It also outlines the process of initiating, administering, and managing drug treatment for this disorder.
Chapter 55, “Contraception” (pp. 959-970)
This chapter examines various methods of contraception and covers drug interactions, selecting the most appropriate agent, and monitoring patient response to contraceptions.
Chapter 56, “Menopause” (pp. 971-994)
This chapter presents various options for menopausal hormone therapy and examines the strengths and limitations of each form of therapy.
Chapter 57, “Osteoporosis” (pp. 985-994)
This chapter covers various options for treating osteoporosis. It also describes proper dosages, potential adverse reactions, and special considerations of each drug.
Chapter 58, “Vaginitis” (pp. 995-1006)
This chapter examines various causes of vaginitis and explores the diagnostic criteria and methods of treatment for the disorder.
Holloway, D. (2010). Clinical update on hormone replacement therapy. British Journal of Nursing, 19(8), 496–504
Note: Retrieved from the Walden Library databases.
This article examines the purpose, components, and administration of hormone replacement therapy (HRT). It also presents benefits, risks, potential side effects, and alternative treatment options of HRT.
Mäkinen, J. I., & Huhtaniemi, I. (2011). Androgen replacement therapy in late-onset hypogonadism: Current concepts and controversies—A mini-review. Gerontology, 57(3), 193–202.
Note: Retrieved from the Walden Library databases.
This article examines the role of testosterone levels in the development of hypogonadism. It also explores health issues that are impacted by testosterone levels and the role of testosterone replacement therapy.
Drugs.com. (2012). Retrieved from http://www.drugs.com/
This website presents a comprehensive review of prescription and over-the-counter drugs including information on common uses and potential side effects. It also provides updates relating to new drugs on the market, support from health professionals, and a drug-drug interactions checker.10
U.S. Preventive Services Task Force. (2014). The Guide to Clinical Preventive Services: Section 2. Recommendations for Adults. Retrieved from http://www.ahrq.gov/professionals/clinicians-providers/guidelines-recommendations/guide/section2.html
This website lists various preventive services available for men and women and provides information about available screenings, tests, preventive medication, and counseling.
Optional Resources
Refer to the Optional Resources listed in Week 1.

Gastrointestinal and Hepatobiliary System

Gastrointestinal and Hepatobiliary System Symptoms of various gastrointestinal (GI) and Hepatobiliary disorders often overlap making diagnosis and treatment challenging.

Gastrointestinal and Hepatobiliary System
Gastrointestinal and Hepatobiliary System

Consider the case of a 21-year-old female who is rushed to the hospital by her roommate. The patient is not conscious enough to describe her symptoms or medical history to the health care provider. However, the roommate is able to share that the patient has experienced abdominal pain for the past three days, as well as vomiting, constipation, and bloating. After unsuccessful attempts at contacting the patient’s family, the roommate decided to bring her in for care.

Gastrointestinal and Hepatobiliary System and the Medical History

At this point, medical history and currently prescribed drugs are unknown. However, this patient requires treatment for symptoms that could be the result of various underlying disorders. As an advanced practice nurse, you could potentially be responsible for this patient’s care. How would you proceed to care for this patient? What type of drug therapy would you recommend not knowing if she is currently taking other prescribed drugs? Are there certain drugs you should avoid in order to prevent a drug-drug interaction?
This week you examine diagnoses for patients with potential GI and Hepatobiliary disorders. You also develop a drug therapy plan based on patient history and diagnosis.
Learning Objectives
students will:
Assess patients with gastrointestinal and hepatobiliary disorders
Develop drug therapy plans based on patient history and diagnosis
Understand and apply key terms, concepts, and principles related to prescribing drugs to treat gastrointestinal and hepatobiliary disorders
Photo Credit: PIXOLOGICSTUDIO/Science Photo Library/Getty Images

Gastrointestinal and Hepatobiliary System Learning Resources

This page contains the Learning Resources for this week. Be sure to scroll down the page to see all of this week’s assigned Learning Resources. To access select media resources, please use the media player below.
Required Readings
Arcangelo, V. P., Peterson, A. M., Wilbur, V., & Reinhold, J. A. (Eds.). (2017). Pharmacotherapeutics for advanced practice: A practical approach (4th ed.). Ambler, PA: Lippincott Williams & Wilkins.
Chapter 28, “Nausea and Vomiting” (pp. 429-446)
This chapter focuses on the etiology of nausea and vomiting, as well as body systems that impact or trigger nausea and vomiting. It also covers various drugs used to treat nausea and vomiting including the process of selecting, administering, and managing drug therapy for patients.
Chapter 29, “Gastroesophageal Reflux Disease and Peptic Ulcer Disease” (pp. 447-462)
his chapter begins with an overview of risk factors, symptoms, and clinical stages of gastroesophageal reflux disease (GERD). It then examines drugs used to treat GERD and peptic ulcer disease (PUD), including proper dosages, possible adverse reactions, contraindications, and special considerations.
Chapter 30, “Constipation, Diarrhea, and Irritable Bowel Syndrome” (pp.465-494)
This chapter begins by exploring disorders associated with constipation and diarrhea, as well as drugs used in treatment. It also covers the pathophysiology of irritable bowel syndrome and related drug therapies.  Chapter 31, “Inflammatory Bowel Disease” (pp. 497-515)
This chapter examines the causes, pathophysiology, and diagnostic criteria of inflammatory bowel disease (IBD), Crohn’s disease, and ulcerative colitis. It also identifies drugs used to treat IBD, including proper dosage, adverse reactions, and special considerations.
Starr, S., & Raines, D. (2011). Cirrhosis: Diagnosis, management, and prevention. American Family Physician, 84 (12), 1353–1359.
Note: Retrieved from the Walden Library databases.
This article examines the clinical presentation, pathophysiology, diagnosis, management, and prevention of cirrhosis. It also provides methods for managing complications of cirrhosis.
Drugs.com. (2012). Retrieved from http://www.drugs.com/
This website presents a comprehensive review of prescription and over-the-counter drugs including information on common uses and potential side effects. It also provides updates relating to new drugs on the market, support from health professionals, and a drug-drug interactions checker.

Gastrointestinal and Hepatobiliary System Required Media

Laureate Education, Inc. (Executive Producer). (2012). Pharmacology for the gastrointestinal system. Baltimore, MD: Author.
This media presentation outlines drug treatment options for disorders of the gastrointestinal system.
Note: The approximate length of this media piece is 2 minutes.
Optional Resources
Refer to the Optional Resources listed in Week 1.

Pharmacotherapy Endocrine Musculoskeletal Disorders

Pharmacotherapy Endocrine Musculoskeletal Disorders Patients with endocrine and musculoskeletal disorders often require long-term treatment and care resulting in the need for extensive patient education.

Pharmacotherapy Endocrine Musculoskeletal Disorders
Pharmacotherapy Endocrine Musculoskeletal Disorders

By appropriately educating patients, advanced practice nurses can assist patients with the management of their disorders. In clinical settings, patients with endocrine and musculoskeletal disorders typically seek treatment for symptoms that pose problems to their everyday lives as ordinary tasks may become difficult to complete. For instance, patients might have difficulty walking short distances, preparing meals, or even running errands. To reduce these symptoms and additional health risks, it is essential to develop drug therapy plans with individual patient factors in mind.
To prepare:
• Select one of the following endocrine or musculoskeletal disorders: thyroid disease, osteoarthritis, rheumatic arthritis, gout, multiple sclerosis, or fibromyalgia.

Pharmacotherapy Endocrine Musculoskeletal Disorders and Types of Drugs

Consider the types of drugs that would be prescribed to patients to treat symptoms associated with this disorder.
• Select one of the following factors: genetics, gender, ethnicity, age, or behavior. Reflect on how this factor might impact the effects of prescribed drugs, as well as any measures you might take to help reduce negative side effects.
With these thoughts in mind:
Post a description of the endocrine or musculoskeletal disorder you selected including types of drugs that would be prescribed to patients to treat associated symptoms. Then, explain how the factor you selected might impact the effects of prescribed drugs, as well as any measures you might take to help reduce negative side effects.

Endocrine and Musculoskeletal System

Endocrine and Musculoskeletal System The endocrine and musculoskeletal systems play important roles in the regulation and coordination of activities throughout the body.

Endocrine and Musculoskeletal System
Endocrine and Musculoskeletal System

When alterations of these systems occur, many patients require long-term drug therapies. In addition to drugs prescribed by their health care providers, patients with these disorders also often take herbal and dietary supplements. According to the American Diabetes Association, 22 percent of diabetic patients use herbal therapy and 31 percent use dietary supplements (American Diabetes Association, 2009). This may impact the effects of prescribed drugs, as well as pose a concern of adverse drug reactions in patients. When treating patients with endocrine and musculoskeletal disorders, it is important to educate patients on associated risks. As an advanced practice nurse prescribing drugs, you must carefully consider all drug, herbal, and dietary therapies prior to finalizing treatment plans.

Endocrine and Musculoskeletal System and Drug Prescription

This week you examine types of drugs prescribed to patients with endocrine and musculoskeletal disorders, as well as the impact of patient factors on the effects of drugs. You also explore ways to improve patient treatment plans including suggested drug therapies. Finally, you examine types of diabetes and the impact of diabetes drugs on patients.
Learning Objectives
students will:
Analyze types of drugs prescribed to treat endocrine and musculoskeletal disorders
Evaluate the impact of patient factors on the effects of prescribed drugs for endocrine and musculoskeletal disorders
Evaluate drug therapy plans to treat endocrine and musculoskeletal disorders
Analyze patient education strategies for treatment and management of endocrine and musculoskeletal disorders
Differentiate types of diabetes
Evaluate the impact of diabetes drugs on patients
Understand and apply key terms, concepts, and principles related to prescribing drugs to treat endocrine and musculoskeletal disorders
Photo Credit: Mark Hatfield/iStock / Getty Images Plus/Getty Images
Learning Resources
This page contains the Learning Resources for this week. Be sure to scroll down the page to see all of this week’s assigned Learning Resources. To access select media resources, please use the media player below.

Endocrine and Musculoskeletal System Required Readings

Arcangelo, V. P., Peterson, A. M., Wilbur, V., & Reinhold, J. A. (Eds.). (2017). Pharmacotherapeutics for advanced practice: A practical approach (4th ed.). Ambler, PA: Lippincott Williams & Wilkins..
Chapter 36, “Osteoarthritis and Rheumatoid Arthritis” (pp. 591-609)
This chapter examines the causes, pathophysiology, and diagnostic criteria of osteoarthritis and rheumatoid arthritis. It then outlines the process of selecting, administering, and managing drug therapy for both disorders.
Chapter 46, “Diabetes Mellitus” (pp. 785-806)
This chapter begins by identifying the causes, pathophysiology, and diagnostic criteria of diabetes mellitus. It then examines the process of selecting, administering, and managing drug therapy for patients with diabetes mellitus.
Chapter 47, “Thyroid Disorders” (pp. 809-822)
This chapter explores the causes, pathophysiology, diagnostic criteria, and administration of drug therapy for patients with thyroid disorders, including hypothyroidism, hyperthyroidism, thyroid nodules, subclinical thyroid disease, and thyroiditis. It also discusses the mechanisms of prescribed drugs, as well as proper dosages and potential adverse reactions.
Ben-Zacharia, A. (2011). Therapeutics for multiple sclerosis symptoms. The Mount Sinai Journal of Medicine, 78 (2), 176–191.
Note: Retrieved from the Walden Library databases.
This article covers the diagnosis, treatment, and management of multiple sclerosis and explores methods for treating other health issues that arise from multiple sclerosis.
Kargiotis, O., Paschali, A., Messinis, L., & Papathanasopoulos, P. (2010). Quality of life in multiple sclerosis: Effects of current treatment options. International Review of Psychiatry, 22(1), 67–82.
Note: Retrieved from the Walden Library databases.
This article examines the process of evaluating and diagnosing patients who present with symptoms of multiple sclerosis and explores treatment and rehabilitation methods.
Peterson, K., Silverstein, J., Kaufman, F., & Warren-Boulton, E. (2007). Management of type 2 diabetes in youth: An update. American Family Physician, 76(5), 658–664.
Note: Retrieved from the Walden Library databases.
This article outlines the process of diagnosing, treating, and managing youths with or at risk of type 2 diabetes. It also suggests methods for body weight management and reducing cardiovascular disease risks.
Drugs.com. (2012). Retrieved from http://www.drugs.com/
This website presents a comprehensive review of prescription and over-the-counter drugs including information on common uses and potential side effects. It also provides updates relating to new drugs on the market, support from health professionals, and a drug-drug interactions checker.
Required Media
Laureate Education, Inc. (Executive Producer). (2012). The endocrine system and diabetes. Baltimore, MD: Author.
This media presentation explores the endocrine system and diabetes including diagnosis and treatment of the disease.
Note: The approximate length of this media piece is 5 minutes.
Laureate Education, Inc. (Executive Producer). (2012). Advanced pharmacology – Mid-course review. Baltimore, MD: Author.
This media is an interactive mid-course review covering course content.
Optional Resources
Refer to the Optional Resources listed in Week 1.

Pharmacokinetics and Pharmacodynamics

Pharmacokinetics and Pharmacodynamics 2 pages
As an advanced practice nurse assisting physicians in the diagnosis and treatment of disorders, it is important to not only understand the impact of disorders on the body, but also the impact of drug treatments on the body.

Pharmacokinetics and Pharmacodynamics
Pharmacokinetics and Pharmacodynamics

The relationships between drugs and the body can be described by pharmacokinetics and pharmacodynamics. Pharmacokinetics describes what the body does to the drug through absorption, distribution, metabolism, and excretion, whereas pharmacodynamics describes what the drug does to the body. When selecting drugs and determining dosages for patients, it is essential to consider individual patient factors that might impact the patient’s pharmacokinetic and pharamcodynamic processes. These patient factors include genetics, gender, ethnicity, age, behavior (i.e., diet, nutrition, smoking, alcohol, illicit drug abuse), and/or pathophysiological changes due to disease. In this Discussion, you reflect on a case from your past clinical experiences and consider how a particular patient’s pharmacokinetic and pharmacodynamic processes altered his or her response to a drug.

To prepare:
Review this week’s media presentation with Dr. Terry Buttaro, as well as Chapter 2 of the Arcangelo and Peterson text, and the Scott article in the Learning Resources.

Principles of Pharmacokinetics and Pharmacodynamics

Consider the principles of pharmacokinetics and pharmacodynamics.
Reflect on your experiences, observations, and/or clinical practices from the last five years. Select a case from the last five years that involves a patient whose individual differences in pharmacokinetic and pharmacodynamic factors altered his or her anticipated response to a drug. When referring to your patient, make sure to use a pseudonym or other false form of identification. This is to ensure the privacy and protection of the patient.
Consider factors that might have influenced the patient’s pharmacokinetic and pharmacodynamic processes such as genetics (including pharmacogenetics), gender, ethnicity, age, behavior, and/or possible pathophysiological changes due to disease.
Think about a personalized plan of care based on these influencing factors and patient history in your case study.
Post a description of the case you selected. Then, describe factors that might have influenced pharmacokinetic and pharmacodynamic processes of the patient from the case you selected. Finally, explain details of the personalized plan of care that you would develop based on influencing factors and patient history in your case.
2: Ethical and Legal Aspects of Prescribing
Responsibilities are given to him on whom trust rests. Responsibility is always a sign of trust.
—James Cash Penney
Nurses have been rated the most trusted professionals in the United States (CDC, 2012). With this trust comes a critical responsibility to maintain ethical and legal practices in order to preserve patient safety when treating patients and prescribing drugs. Since the scope of practice for advanced practice nurses is broadening, you will likely encounter new and complex ethical challenges in your clinical settings.
This week, you explore ethical and legal implications of prescribing drugs including disclosure, nondisclosure, and prescriptive authority. You also examine the process of writing prescriptions to avoid prescription drug errors.

Pharmacokinetics and Pharmacodynamics Learning Objectives

students will:
Evaluate ethical and legal implications related to prescribing drugs
Analyze ethical and legal practices of prescribing drugs
Evaluate ethical and legal implications of disclosure and nondisclosure
Analyze the process of writing prescriptions to avoid medication errors
Understand and apply key terms, concepts, and principles related to ethical and legal aspects of prescribing
Photo Credit: erhui1979/DigitalVision Vectors/Getty Images
Learning Resources
This page contains the Learning Resources for this week. Be sure to scroll down the page to see all of this week’s assigned Learning Resources. To access select media resources, please use the media player below.
Required Readings
Arcangelo, V. P., Peterson, A. M., Wilbur, V., & Reinhold, J. A. (Eds.). (2017). Pharmacotherapeutics for advanced practice: A practical approach (4th ed.). Ambler, PA: Lippincott Williams & Wilkins.
Chapter 1, “Issues for the Practitioner in Drug Therapy” (pp. 3–14)
This chapter introduces issues relating to drug therapy such as adverse drug events and medication adherence. It also explores drug safety, the practitioner’s role and responsibilities in prescribing, and prescription writing.
Chapter 59, “The Economics of Pharmacotherapeutics” (pp. 1009-1018)
This chapter analyzes the costs of drug therapy to health care systems and society and explores practice guideline compliance and current issues in medical care.
Chapter 60, “Integrative Approaches to Pharmacotherapy—A Look at Complex Cases” (pp. 1021-1036)
This chapter examines issues in individual patient cases. It explores concepts relating to evaluation, drug selection, patient education, and alternative treatment options.
Due to the importance of ethical and legal considerations in advanced practice nursing, several resources have been provided for your reference.
Crigger, N., & Holcomb, L. (2008). Improving nurse practitioner practice through rational prescribing. The Journal for Nurse Practitioners, 4(2), 120–125.
Note: Retrieved from the Walden Library databases.
This article explores issues relating to prescription drugs, specifically the frequency in which drugs are prescribed to patients. It also examines factors to consider before beginning drug therapy plans with patients.
Philipsen, N. C., & Soeken, D. (2011). Preparing to blow the whistle: A survival guide for nurses. The Journal for Nurse Practitioners, 7(9), 740–746.
Note: Retrieved from the Walden Library databases.
This article examines issues that nurses encounter when reporting errors in medical settings. It also outlines the role of ethics and the responsibility of nurses to notify all individuals who are impacted by a medical error.
American Nurses Association. (2001). Code of ethics for nurses with interpretive statements. Nursing World. Retrieved from http://www.nursingworld.org/MainMenuCategories/EthicsStandards/CodeofEthicsforNurses/Code-of-Ethics-For-Nurses.html
This article outlines ethical standards in the nursing profession and identifies nine provisions of care that must be adhered to by all nurses.
Anderson, P., & Townsend, T. (2010). Medication errors: Don’t let them happen to you. American Nurse Today, 5(3), 23–28. Retrieved from https://americannursetoday.com/medication-errors-dont-let-them-happen-to-you/
This article examines factors that lead to medication errors as well as consequences of these errors on patients and nurses. It also recommends methods for avoiding and eliminating medication errors.
Drug Enforcement Administration. (n.d.). Mid-level practitioners authorization by state. Retrieved from August 23, 2012, http://www.deadiversion.usdoj.gov/drugreg/practioners/index.html
This website outlines the schedules for controlled substances, including prescriptive authority for each schedule.
Drug Enforcement Administration. (2006.). Practitioner’s manual. Retrieved from http://www.deadiversion.usdoj.gov/pubs/manuals/pract/index.html

Pharmacokinetics and Pharmacodynamics Resources

This manual is a resource for practitioners who prescribe, dispense, and administer controlled substances. It provides information on general requirements, security issues, recordkeeping, prescription requirements, and addiction treatment programs.
Drugs.com. (2012). Retrieved from http://www.drugs.com/
This website presents a comprehensive review of prescription and over-the-counter drugs including information on common uses and potential side effects. It also provides updates relating to new drugs on the market, support from health professionals, and a drug-drug interactions checker.
Institute for Safe Medication Practices. (2012). ISMP’s list of error-prone abbreviations, symbols, and dose designations. Retrieved from http://www.ismp.org/Tools/errorproneabbreviations.pdf
This website provides a list of prescription writing abbreviations that might lead to misinterpretation, as well as suggestions for preventing resulting errors.
Optional Resources
Byrne, W. (2011). U.S. nurse practitioner prescribing law: A state-by-state summary. Medscape Nurses. Retrieved from http://www.medscape.com/viewarticle/440315
Drug Enforcement Administration. (n.d.). Code of federal regulations. Retrieved August 23, 2012, from http://www.deadiversion.usdoj.gov/21cfr/cfr/1300/1300_01.htm
Drug Enforcement Administration. (n.d.). Registration. Retrieved August 23, 2012, from http://www.deadiversion.usdoj.gov/Registration.html
In addition, refer to the Optional Resources listed in Week 1.