Cancer and Women’s and Men’s Health

Cancer and Women's and Men's Health
Cancer and Women’s and Men’s Health

Cancer and Women’s and Men’s Health

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Application: Cancer and Women’s and Men’s Health

The American Cancer Society estimates that by the end of 2012, more than 226,000 women will be diagnosed with breast cancer and more than 241,000 men will be diagnosed with prostate cancer (American Cancer Society, 2012a; American Cancer Society 2012b). With such prevalence of women’s and men’s cancers, patient education and preventive services are essential. In clinical settings, advanced practice nurses must assist physicians in educating patients on risk factors, preventive services, and for patients diagnosed with cancer, on potential drug treatments. The clinical implications of women’s and men’s cancer greatly depend on early detection, which is primarily achieved through preventive services. In this Assignment, you consider the short-term and long-term implications of cancer and drug treatments associated with women’s and men’s health, as well as appropriate preventive services.

To prepare:
•Select a type of cancer associated with women’s or men’s health such as breast, cervical, or ovarian cancer in women and prostate cancer in men.
•Locate and review articles examining the type of cancer you selected.
•Review the U.S. Preventive Services Task Force article in the Learning Resources. Think about available preventive services that providers might recommend for patients at risk of this type of cancer.
•Select two of the following factors: genetics, gender, ethnicity, age, or behavior. Reflect on how these factors might impact decisions related to preventive services.
•Consider drug treatment options for patients diagnosed with the type of cancer you selected including short-term and long-term implications of the treatments.

To complete:

Write a 2- to 3- page paper that addresses the following:
•Describe available preventive services that providers might recommend for patients at risk of the type of cancer you selected.
•Explain how the factors you selected might impact decisions related to preventive services.
•Describe drug treatment options for patients diagnosed with the type of cancer you selected. Explain the short-term and long-term implications of these treatments.

SAMPLE ANSWER

Introduction

Research indicates that 2 million of men in the US are prostate cancer survivors. It is the most common cancer among the male, followed by skin cancer. According to the American Cancer Society, there are about 220,800 cases of prostate cancer annually, which claims about 27,540 lives every year. According to statistics, it is estimated that every one male in every seven will be diagnosed with prostate cancer in his lifetime. Prostate cancer is the cancer of the prostate gland, which is found in males. The gland is located below the urinary bladder. The size of the gland changes with age, and has been found to grow rapidly in puberty. This rapid growth in puberty is fueled by increased concentration on male hormones (androgens). The medical terminology of cancer in the prostate gland is referred to adenocarcinoma. Other types of prostate gland include sarcomas, cell carcinomas, transitional cell carcinomas, and neuroendocrine tumors. Some of the cancer spread rapidly whereas others grow slowly (Burdelski et al., 2015).

Preventive services

The early prostate cancer is usually asymptomatic and is known to have no symptoms. However, at an advanced stage, prostate cancers have symptoms such as difficulties when passing urine due to a weakened urine system. The patient tends to have frequent urination especially during the night. In some cases, blood traces are present in urine. Additionally, the male individual could suffer from erectile dysfunction, chronic pain in the hips, spine, and chest. The patient may also have weakness and numbness in the feet and legs, loss of bowel or bladder control due to the altered nervous system, especially the spinal cord (Ingersoll et al., 2015).

Early screening is one of the preventive measures applied in management of prostate cancer. Early detection is important because it facilitates a quick application of intervention to protect the patient from further complications. Prostate cancer screening is usually done by measuring the prostrate-specific antigen (PSA) in the patient’s concentration. Digital rectal Exam has also been widely used where the physician inserts their finger into the rectum to evaluate the size and texture of the prostate gland. Some medications proposed to reduce risk for prostate cancer including, 5-alpha reductase inhibitors that inhibits the conversion of the enzyme testosterone to dihydrotestosterone (DHT) enzymes that induces prostate cancer. Recent studies have identified an effective prostate cancer vaccine known as Sipuleucel-T. The vaccine works by boosting the immune system, which fights prostate cancer cells (Thalgott et al., 2015).

The current evidence based risk factors include embracing a healthy lifestyle. This implies that the individual should feed on a low fat diet by avoiding high intake of meat, oils, dairy products, and nuts. This is because high intake of fats is associated with high risk of prostate cancer. Elderly males should be advised to consume more plant meals than animal meals. More fruits, vitamin, mineral supplements, and seafood should be included in the diet. Physical activeness must be encouraged among the individuals. Studies indicate that active people have low risk of prostate cancer. This is because exercising help in keeping the body in good shape (Gupta et al., 2015).

Risk factors influence of preventive services

There are risk factors that affect prostate cancer. Risk factor includes factors that aggravate chances of developing the healthcare complication. The different types of cancer have varying risk factors with a few having unknown risk factors. One of the main risk factors for prostate cancer includes age, geographical location, ethnic background, sexually transmitted diseases, genetic factors, vasectomy, and exposures in the work place, lifestyles, and family history. This paper evaluates the two main risk factors that affect the decisions for preventive care (Tomioka et al., 2015).

Age is one of the main risk factors of prostate cancer, which is more common in men above 65 years of age, but very rare in the young male of below 40 years. This age group often lack adequate knowledge and information. This acts as barrier to the adoption of preventive services such as early screening, life style modification and medication adherence. Prostate cancer has also been found to be common in African-American men than in other ethnic groups. Prostate cancer is less common in the Latino’s and Hispanics. Cultural values and beliefs are key hindrances to the adoption and integration of the aforementioned preventive services (Nakazawa et al., 2015).

In some community, such as African American, it is actually a taboo to discuss genitalia matters in public, and especially so if the physician is of  the opposite sex and of younger age than the service user. This implies that the disease is detected late, and interventions are given when the disease   has reached its unmanageable stage. Other barriers associated with these two risk factors are time constraints and low staff levels, which results to an unanimous theme during counseling on current evidence, based practices of preventive services (Burdelski et al., 2015).

Drug treatment for prostate cancer

If the prostate cancer is diagnosed and staged effectively, it is important for the patient to empower to make informed decisions. Several drug treatment options are associated treatments with prostate cancer. These include active surveillance or watchful waiting where prostate cancer growth is monitored closely with DREs and PSA. This is because some prostate cancers are benign and may not need to treat the condition. Radiation therapy involves the use of high energy to destroy the cancerous cells. Cryosurgery is used to treat the first prostate cancer stage and involves the freezing of the cancerous cells (Gupta et al., 2015).

Chemotherapy is often used as anti-cancer drugs, which are often injected in the vein in the blood circulatory system. This therapy is important if the cancer has spread throughout the other body organs. Hormone therapy involves the use of hormone blockers or suppression therapy to suppress the conversion of testosterone to cancer inducing enzyme. Bone directed therapy and vaccine therapy have been successful in treating prostate cancer. The decision of treatment should be based on the patient’s general health condition, age, stage of cancer, preferences and the expected side effects.

Short term and long-term implication of prostate cancer

Short-term effects include fatigue and extreme tiredness. In some cases, fecal inconsistencies may occur due to the inflammation if the rectum. This often results in urgency to urinate, diarrhea, cramps, and blood in the patients stool. Other short term effects  include the possibilities of  blood transfusion and pulmonary embolism In some cases, the issue of erectile dysfunction can occur, low libido and  infertility and urinary leakage (Burdelski et al., 2015).

The long-term side effects   include erectile dysfunction, narrowing of the joint between the urethra and the urinary bladder, which causes the frequent urge of urination. Men under hormonal therapies are at risk of muscle and mineral loss (osteoporosis) which makes the patient become more vulnerable to fractures. The most common long-term effect is emotional instability, which is associated with loss of fertility and erectile dysfunction. Most men diagnosed with erectile dysfunction tend to be angry, anxious and in denial. Their self-esteem is usually reduced especially if the illness affects their sex life and finances (Gupta et al., 2015).

References

Burdelski, C., Menan, D., Tsourlakis, M., Kluth, M., Hube-Magg, C., & Melling, N. et al. (2015). The prognostic value of SUMO1/Sentrin specific peptidase 1 (SENP1) in prostate cancer is limited to ERG-fusion positive tumors lacking PTEN deletion. BMC Cancer, 15(1). https://www.doi:10.1186/s12885-015-1555-8

Gupta, D., Trukova, K., Popiel, B., Lammersfeld, C., & Vashi, P. (2015). The Association between Pre-Treatment Serum 25-Hydroxyvitamin D and Survival in Newly Diagnosed Stage IV Prostate Cancer. PLOS ONE, 10(3), e0119690.                                                                   https://www.doi:10.1371/journal.pone.0119690

Ingersoll, M., Lyons, A., Muniyan, S., D’Cunha, N., Robinson, T., & Hoelting, K. et al. (2015). Novel Imidazopyridine Derivatives Possess Anti-Tumor Effect on Human Castration-Resistant Prostate Cancer Cells. PLOS ONE, 10(6), e0131811.                              https://www.doi:10.1371/journal.pone.0131811

Nakazawa, T., Tateoka, K., Saito, Y., Abe, T., Yano, M., & Yaegashi, Y. et al. (2015). Analysis of Prostate Deformation during a Course of Radiation Therapy for Prostate Cancer. PLOS ONE, 10(6), e0131822.              https://www.doi:10.1371/journal.pone.0131822

Thalgott, M., Rack, B., Eiber, M., Souvatzoglou, M., Heck, M., & Kronester, C. et al. (2015). Categorical versus continuous circulating tumor cell enumeration as early surrogate marker for therapy response and prognosis during docetaxel therapy in metastatic prostate cancer patients. BMC Cancer, 15(1). https://www.doi:10.1186/s12885-015-1478-4

Tomioka, A., Tanaka, N., Yoshikawa, M., Miyake, M., Anai, S., & Chihara, Y. et al. (2015). Risk factors of PSA progression and overall survival in patients with localized and locally advanced prostate cancer treated with primary androgen deprivation therapy. BMC Cancer, 15(1). https://www.doi:10.1186/s12885-015-1429-0

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