Down Syndrome a Chromosomal Disorder Down syndrome is a chromosomal disorder caused when an error in cell division results in an extra 21st chromosome.
There can be impairments in cognitive ability and physical growth, mild to moderate developmental disabilities, and a higher risk of some health problems. Down syndrome is a chromosomal condition that is associated with intellectual disability, a characteristic facial appearance, and weak muscle tone (hypotonia) in infancy. All affected individuals experience cognitive delays, but the intellectual disability is usually mild to moderate. Digestive abnormalities, such as a blockage of the intestine, are less common.
